In myotonic dystrophy, a group of RNA-binding factors — the Muscleblind-like proteins — are sequestered by transcripts containing expanded trinucleotide repeats; this sequestration disrupts their proposed physiological function as regulators of alternative splicing. Now, exciting data suggest that Muscleblind-like proteins are also involved in the localization of integrin mRNA.
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de Andrade, G., Jansen, RP. Moving with Muscleblind. Nat Cell Biol 7, 1155–1156 (2005). https://doi.org/10.1038/ncb1205-1155
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DOI: https://doi.org/10.1038/ncb1205-1155
