A functional bipolar spindle is indispensible for the accurate segregation of chromosomes at mitosis. The centrosomal protein and polo-like kinase-1 (Plk1) substrate Kizuna (Kiz), has now been shown to have a novel function in maintaining spindle-pole integrity and spindle bipolarity.
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Cizmecioglu, O., Hoffmann, I. Kizuna takes pole position. Nat Cell Biol 8, 1050–1051 (2006). https://doi.org/10.1038/ncb1006-1050
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DOI: https://doi.org/10.1038/ncb1006-1050
