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Rocket-based motility: a universal mechanism?

Nature Cell Biology volume 1, pages E29–E31 (1999)Cite this article

Abstract

Similarities between actin polymerization at the leading edges of motile mammalian cells and the motile actin tail of the bacterium Listeria monocytogenes are centred on the Arp2/3 complex. Eukaryotic cells use multiple pathways to modulate actin polymerization, while Listeria short-circuits these pathways to produce constitutive actin polymerization.

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Figure 1: Arp2/3 complex and actin incorporation at the leading edges of cells.
Figure 2: Eukaryotic cells and LIsteria may use similar mechanisms to induce actin polymerization.
Figure 3: Listeria ActA has homology to WASP-family proteins and to zyxin/vinculin.

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Authors and Affiliations

  1. Department of Biochemistry University of Birmingham, Birmingham, B15 2TT, UK

    Laura M. Machesky

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  1. Laura M. Machesky
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Correspondence to Laura M. Machesky.

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Machesky, L. Rocket-based motility: a universal mechanism?. Nat Cell Biol 1, E29–E31 (1999). https://doi.org/10.1038/10020

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