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Moving on Up: Upgrading from an ABSL2 to ABSL3 Facility

Lab Animal volume 33, pages 30–34 (2004)Cite this article

Abstract

Renewed interest in bioterrorism-related research has resulted in the need for more ABSL3/4 facilities. In some cases, money has been available to build new facilities, but more often institutions are faced with retrofitting existing facilities to meet the higher containment standards. The author discusses several factors that must be addressed before beginning this type of renovation project.

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Figure 1: Ping-pong-ball room pressure indicators provide a simple visual indicator of relative room pressures.
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References

  1. 42 CFR Part 73: Possession, Use, and Transfer of Select Agents and Toxins.

  2. Antiterrorism and Effective Death Penalty Act of 1996, Sec. 511. Enhanced Penalties and Control of Biologic Agents.

  3. 42 CFR Part 72: Interstate Shipment of Etiologic Agents. Appendix A. Select Agents.

  4. USA PATRIOT Act.

  5. Public Health Security and BioTerrorism Preparedness and Response Act of 2002, Title II—Enhancing Controls on Dangerous Biological Agents and Toxins, Subparts A, B, C.

  6. USDA Agricultural Bioterrorism Protection Act of 2002.

  7. US Department of Health and Human Services, Centers for Disease Control and Prevention, and National Institutes of Health. Biosafety in Microbiological and Biomedical Laboratories 4th edn (eds Richmond, J.Y. & McKinney, R.W.) (US Government Printing Office, Washington, DC, 1999).

  8. Institute for Laboratory Animal Resources, National Research Council. Guide for the Care and Use of Laboratory Animals (National Academy Press, Washington DC, 1996).

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Author information

Authors and Affiliations

  1. Hitt is at GRC/NIA/NIH, Comparative Medicine Section, Baltimore, MD.,

    Nancy D. Hitt DVM, MS

Authors
  1. Nancy D. Hitt DVM, MS
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Correspondence to Nancy D. Hitt DVM, MS.

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Hitt, N. Moving on Up: Upgrading from an ABSL2 to ABSL3 Facility. Lab Anim 33, 30–34 (2004). https://doi.org/10.1038/laban1104-30

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  • DOI: https://doi.org/10.1038/laban1104-30

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