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Prevalence of erectile dysfunction among Chinese men with type 2 diabetes mellitus

International Journal of Impotence Research volume 22, pages 310–317 (2010)Cite this article

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Abstract

The aims of this study were to investigate the prevalence of ED in Chinese men with type 2 diabetes mellitus, and evaluate the efficacy and safety of sildenafil citrate in these patients. Patients from 42 outpatient diabetes clinics with type 2 diabetes mellitus and ED as defined by the International Index of Erectile Function (IIEF)-5 were studied. Participants with ED received three doses (100 mg each) of sildenafil citrate for use over 3 months. Efficacy of sildenafil citrate was assessed using the IIEF-5 and the Global Efficacy Questionnaire (GEQ). Adverse events were recorded by patients in a daily diary. A total of 5477 participants were evaluated, and 75.2% had ED. Age, duration of diabetes and glycosylated hemoglobin (HbA1c) >6.5% were independently and significantly associated with the presence and degree of ED. Patients who received pharmacotherapy (N=389) reported significant improvements. The rate of erections as determined by the GEQ was also significantly improved following treatment. ED is a common complication in Chinese men with type 2 diabetes mellitus, and certain risk factors are associated with the presence of ED and severity. Sildenafil citrate is a safe and effective treatment for these patients.

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Acknowledgements

This work was supported by Independent Research Fund of Pfizer Pharmaceuticals Limited (no. PRC-IZ-02-002).

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  1. Department of Endocrinology, Chinese PLA General Hospital, Beijing, China

    G Yang, C Pan & J Lu

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Correspondence to C Pan.

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The Collaborative Study Group for multicenter clinical study of erectile dysfunction in Chinese men with type 2 diabetes in China.

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Yang, G., Pan, C. & Lu, J. Prevalence of erectile dysfunction among Chinese men with type 2 diabetes mellitus. Int J Impot Res 22, 310–317 (2010). https://doi.org/10.1038/ijir.2010.21

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