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  • Letter to the Editor
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Reply to ‘Efficacy of changing testosterone gel preparations (Androgel or Testim) among suboptimally responsive hypogonadal men’

International Journal of Impotence Research volume 20, page 332 (2008)Cite this article

The authors' are grateful to Dr Morgentaler and the editorial team of the International Journal of Impotence Research for their important insights into this research. A few points however require clarification.

Prior to treatment with either gel, all patients had clinical symptoms of hypogonadism and a total serum testosterone (T) level of <300 ng dl−1. Among patients initially treated with Testim, the mean T was 544 ng dl−1 and the proportion with T <300 ng dl−1 was only 15%. Following substitution by Androgel, mean T was 522 ng dl−1 and the proportion with sub-therapeutic T levels (<300 ng dl−1) increased to 27%. This does not mean that ‘73% of men whose original T levels were suboptimal with Testim had improved T concentrations with Androgel’ as suggested by Dr Morgentaler. In fact, our data suggest that an additional 12% had sub-therapeutic T levels following a switch to Androgel.

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Authors and Affiliations

  1. Division of Urology, Mount Sinai Hospital and Women's College Hospital, University of Toronto, Toronto, ON, Canada

    E D Grober

  2. Scott Department of Urology, Baylor College of Medicine, Houston, TX, USA. E-mail: ethan.grober@utoronto.ca,

    L I Lipshultz

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  1. E D Grober
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Grober, E., Lipshultz, L. Reply to ‘Efficacy of changing testosterone gel preparations (Androgel or Testim) among suboptimally responsive hypogonadal men’. Int J Impot Res 20, 332 (2008). https://doi.org/10.1038/ijir.2008.6

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