Abstract
The frequency of DNA aneuploidy was investigated by flow cytometry in 156 colorectal adenomas including 56 associated with 36 synchronous adenocarcinomas. Nine of 156 adenomas (6%) were DNA aneuploid. DNA aneuploidy correlated with increasing size (P less than 0.005) and histopathological type P less than 0.05) but not with dysplasia. Adenomas in associated with a synchronous adenocarcinoma did not have an increased incidence of DNA aneuploidy. Adenocarcinomas found in association with adenomas tend to have a lower incidence of DNA aneuploidy then the generality of colorectal cancers.
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Quirke, P., Fozard, J., Dixon, M. et al. DNA aneuploidy in colorectal adenomas. Br J Cancer 53, 477–481 (1986). https://doi.org/10.1038/bjc.1986.75
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DOI: https://doi.org/10.1038/bjc.1986.75
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