Evo-devo meets systems biology.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Quantitative Genetics, Pleiotropy, and Morphological Integration in the Dentition of Papio hamadryas
Evolutionary Biology Open Access 07 March 2009
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1038%2F451658a/MediaObjects/41586_2008_Article_BF451658a_Fig1_HTML.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1038%2F451658a/MediaObjects/41586_2008_Article_BF451658a_Fig2_HTML.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1038%2F451658a/MediaObjects/41586_2008_Article_BF451658a_Fig3_HTML.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1038%2F451658a/MediaObjects/41586_2008_Article_BF451658a_Fig4_HTML.jpg)
![](http://media.springernature.com/m312/springer-static/image/art%3A10.1038%2F451658a/MediaObjects/41586_2008_Article_BF451658a_Fig5_HTML.jpg)
References
Rumi, Mawlana Jalaluddin The Elephant in the Dark Room (13th cent.) in Mathnawi-yi ma'nawi (Masnavi) III 1259–1268 (ed. Nicholson, R. A.) (London 1925–1940).
Rutherford, S. L. & Lindquist, S. Nature 396, 336–342 (1998).
Bridgham, J. T., Carroll, S. M. & Thornton, J. W. Science 312, 97–101 (2006).
Wray, G. A. et al. Mol. Biol. Evol. 20, 1377–1419 (2003).
Pearl, J. Causality: Models, Reasoning, and Inference (Cambridge Univ. Press, 2000).
Guido, N. J. et al. Nature 439, 856–860 (2006).
Raff, R. A. Nature Rev. Genet. 8, 911–920 (2007).
Janvier, P. Early Vertebrates (Oxford Univ. Press, 1996).
Witmer, L. M. in Functional Morphology in Vertebrate Paleontology (ed. Thomason, J. J. ) 19–33 (Cambridge Univ. Press, New York, 1995).
Trinajstic, K., Marshall, C., Long, J. & Bifield, K. Biol. Lett. 3, 197–200 (2007).
Donoghue, P. C. et al. Nature 442, 680–683 (2006).
Stelling, J., Sauer, U., Szallasi, Z., Doyle, F. J. III & Doyle, J. Cell 118, 675–685 (2004).
Martinez-Arias, A. & Lawrence, P. A. Nature 313, 639–642 (1985).
Lumsden, A. & Keynes, R. Nature 337, 424–428 (1989).
Larsen, C. W., Zeltser, L. M. & Lumsden, A. J. Neurosci. 21, 4699–4711 (2001).
Koentges, G. & Lumsden, A. Development 122, 3229–3242 (1996).
Matsuoka, T. et al. Nature 436, 347–355 (2005).
Gu, H., Marth, J. D., Orban, P. C., Mossmann, H. & Rajewsky, K. Science 265, 103–106 (1994).
Huang, R., Zhi, Q., Patel, K., Wilting, J. & Christ, B. Development 127, 3789–3794 (2000).
Balciunas, D. et al. PLoS Genet. 2, e169 (2006).
Ogino, H., McConnell, W. B. & Grainger, R. M. Nature Protocols 1, 1703–1710 (2006).
Lois, C., Hong, E. J., Pease, S., Brown, E. J. & Baltimore, D. Science 295, 868–872 (2002).
Davidson, E. H. The Regulatory Genome: Gene Regulatory Networks in Development and Evolution (Academic Press/Elsevier, San Diego, 2006).
Kirschner, M. & Gerhart, J. Proc. Natl Acad. Sci. USA 95, 8420–8427 (1998).
Abouheif, E. & Wray, G. A. Science 297, 249–252 (2002).
Freitas, R., Zhang, G. & Cohn, M. J. Nature 442, 1033–1037 (2006).
Carr, J. L., Shashikant, C. S., Bailey, W. J. & Ruddle, F. H. J. Exp. Zool. 280, 73–85 (1998).
Keys, D. N. et al. Science 283, 532–534 (1999).
Prud'homme, B., Gompel, N. & Carroll, S. B. Proc. Natl Acad. Sci. USA 104 (suppl. 1), 8605–8612 (2007).
Ronshaugen, M., McGinnis, N. & McGinnis, W. Nature 415, 914–917 (2002).
Tietjen, I. et al. Neuron 38, 161–175 (2003).
Abzhanov, A. et al. Nature 442, 563–567 (2006).
Hafner, M. et al. Methods 44, 3–12 (2008).
Friedman, N. Science 303, 799–805 (2004).
Pournara, I. & Wernisch, L. Bioinformatics 20, 2934–2942 (2004).
Hansen, A., Ott, S. & Koentges, G. Genome Inform. 15, 141–150 (2004).
Stark, A. et al. Nature 450, 219–232 (2007).
Istrail, S. & Davidson, E. H. Proc. Natl Acad. Sci. USA 102, 4954–4959 (2005).
Tsong, A. E., Tuch, B. B., Li, H. & Johnson, A. D. Nature 443, 415–420 (2006).
Faro-Trindade, I. & Cook, P. R. Biochem. Soc. Trans. 34, 1133–1137 (2006).
Maniatis, T. et al. Cold Spring Harb. Symp. Quant. Biol. 63, 609–620 (1998).
Arnosti, D. N. & Kulkarni, M. M. J. Cell. Biochem. 94, 890–898 (2005).
Smith, J., Theodoris, C. & Davidson, E. H. Science 318, 794–797 (2007).
Kmita, M. & Duboule, D. Science 301, 331–333 (2003).
Damle, S., Hanser, B., Davidson, E. H. & Fraser, S. E. Dev. Biol. 299, 543–550 (2006).
Roure, A. et al. PLoS One 2, e916 (2007).
Pennacchio, L. A. et al. Nature 444, 499–502 (2006).
Chen, J. C., Ramachandran, R. & Goldhamer, D. J. Dev. Biol. 245, 213–223 (2002).
Alon, U. An Introduction to Systems Biology: Design Principles of Biological Circuits (Chapman & Hall, 2006).
Akam, M. Curr. Biol. 8, R676–R678 (1998).
Weatherbee, S. D. et al. Curr. Biol. 9, 109–115 (1999).
Gehring, W. J. Zoology 104, 171–183 (2001).
Blake, W. J., Kærn, M., Cantor, C. R. & Collins, J. J. Nature 422, 633–637 (2003).
Beckers, J., Gérard, M. & Duboule, D. Dev. Biol. 180, 543–553 (1996).
Tian, J. et al. Nature 432, 1050–1054 (2004).
Hittinger, C. T. & Carroll, S. B. Nature 449, 677–681 (2007).
Raser, J. M. & O'Shea, E. K. Science 309, 2010–2013 (2005).
Kavanagh, K. D., Evans, A. R. & Jernvall, J. Nature 449, 427–432 (2007).
Wernet, M. F. et al. Nature 440, 174–180 (2006).
Nicodemi, M. & Prisco, A. Phys. Rev. Lett. 98, 108104 (2007).
Acknowledgements
I thank Keith Vance, Sascha Ott and Per Ahlberg for discussions. I gratefully acknowledge advice from Sheila Canby (British Museum) about Persian miniatures and Rumi. Benoît Junod, curator at the Aga Khan Trust for Culture in Geneva, provided the photograph of the elephant. I apologize to my colleagues for not being able to cite all relevant publications. Work in my laboratory is funded by the Wellcome Trust, the Human Frontier Science Program, the ARC, ConquerChiari and the BBSRC.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Koentges, G. Evolution of anatomy and gene control. Nature 451, 658–663 (2008). https://doi.org/10.1038/451658a
Published:
Issue Date:
DOI: https://doi.org/10.1038/451658a
This article is cited by
-
Quantitative Genetics, Pleiotropy, and Morphological Integration in the Dentition of Papio hamadryas
Evolutionary Biology (2009)
-
Teeth in double trouble
Nature (2008)