Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Reversal of fortune for nascent proteins

The demonstration of a way in which cytomegalovirus can evade immune surveillance also points to a mechanism by which abnormal proteins, once synthesized, can be degraded.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Lewin, D. I. J. NIH Res. 7, 49–53 (1995).

    ADS  Google Scholar 

  2. Wiertz, E. J. H. J. et al. Nature 384, 432–438 (1996).

    Article  ADS  CAS  Google Scholar 

  3. Wiertz, E. J. H. J. et al. Cell 84, 769–779 (1996).

    Article  CAS  Google Scholar 

  4. Hanein, D. et al. Cell 87, 721–732 (1996).

    Article  CAS  Google Scholar 

  5. Hurtley, S. M. & Helenius, A. Annu. Rev. Cell Biol. 5, 277–307 (1989).

    Article  CAS  Google Scholar 

  6. Sidman, C. Cell 23, 379–389 (1981).

    Article  CAS  Google Scholar 

  7. Bonifacino, J. S. & Klausner, R. D. in Cellular Proteolytic Systems (eds Ciechanover, A. & Schwartz, A. L.) 137–160 (Wiley-Liss, New York, 1994).

    Google Scholar 

  8. Jensen, T. J. et al. Cell 83, 129–135 (1995).

    Article  CAS  Google Scholar 

  9. Ward, C. L., Omura, S. & Kopito, R. R. Cell 83, 121–127 (1995).

    Article  CAS  Google Scholar 

  10. Biederer, T., Volkwein, C. & Sommer, T. EMBO J. 15, 2069–2076 (1996).

    Article  CAS  Google Scholar 

  11. Qu, D., Teckman, J. H., Omura, S. & Perlmutter, D. H. J. Biol. Chem. 271, 22791–22795 (1996).

    Article  CAS  Google Scholar 

  12. Hiller, M. M., Finger, A., Schweiger, M. & Wolf, D. H. Science 20, 1725–1728 (1996).

    Article  ADS  Google Scholar 

  13. McCracken, A. A. & Brodsky, J. L. J. Cell Biol. 132, 291–298 (1996).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bonifacino, J. Reversal of fortune for nascent proteins. Nature 384, 405–406 (1996). https://doi.org/10.1038/384405a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/384405a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing