Multiple small biological samples can be simultaneously prepared for RT-PCR by magnetically isolating mRNA and synthesizing cDNA in 96-well plates. The resulting accuracy, high throughput and ease of use facilitate commercial and clinical applications.
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Oaklander, A., Ekenberg, S. Small-scale magnetic isolation of mRNA and synthesis of cDNA in 96-well plates. Nature 371, 631–632 (1994). https://doi.org/10.1038/371631a0
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DOI: https://doi.org/10.1038/371631a0