Protein engineering has made it possible to combine the binding sites of murine antibodies with human antibody regions. Antibodies constructed in this way have important advantages for therapy.
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Co, M., Queen, C. Humanized antibodies for therapy. Nature 351, 501–502 (1991). https://doi.org/10.1038/351501a0
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DOI: https://doi.org/10.1038/351501a0
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