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Cell biology

Bacteria thread the needle

When bacteria attack another organism, one of the first steps is the injection of 'virulence effector proteins' into its cells. Two of the main players in such a system have been caught in action.

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Figure 1: Formation of the complex between SicP (the chaperone) and SptP (the Salmonella effector protein).
Figure 2: Model of chaperone-assisted type III secretion in Salmonella.

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Smith, C., Hultgren, S. Bacteria thread the needle. Nature 414, 29–31 (2001). https://doi.org/10.1038/35102139

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