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Diabetes

Gene therapy for rats and mice

Nature volume 408, pages 420–421 (2000)Cite this article

Delivery of an insulin-encoding gene into diabetic rats and mice has helped them to regulate their blood glucose levels. But there are still obstacles to overcome before this approach can be used in humans.

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References

  1. Eisenberth, G. S., Ziegler, A. G. & Colman, P. A. in Joslin's Diabetes Mellitus 13th edn (eds Kahn, C. R. & Weir, G. C.) 216–239 (Lea & Febiger, Philadelphia, 1994).

    Google Scholar 

  2. Shapiro, A. M. et al. N. Engl. J. Med. 343, 230– 238 (2000).

    Article  CAS  Google Scholar 

  3. Lee, H. C., Kim, S.-J, Kim, K.-S, Shin, H.-C & Yoon, J.-W Nature 408, 483– 488 (2000).

    Article  ADS  CAS  Google Scholar 

  4. Pozzilli, P. et al. Immunol. Today 14, 193 ( 1993).

  5. Rhodes, C. J. in Diabetes Mellitus: A Fundamental and Clinical Text 2nd edn (eds LeRoith, D., Taylor, S. I. & Olefsky, J. M.) 20–37 (Lippincott Williams & Wilkins, Philadelphia, 2000).

    Google Scholar 

  6. Shoelson, S. E. & Halban, P. A. in Joslin's Diabetes Mellitus 13th edn (eds Kahn, C. R. & Weir, G. C.) 29–55 (Lea & Febiger, Philadelphia, 1994).

    Google Scholar 

  7. Rosenzweig, J. L. in Joslin's Diabetes Mellitus 13th edn (eds Kahn, C. R. & Weir, G. C.) 460–488 (Lea & Febiger, Philadelphia, 1994).

    Google Scholar 

  8. Brink, S. J. in Diabetes Mellitus: A Fundamental and Clinical Text 2nd edn (eds LeRoith, D., Taylor, S. I. & Olefsky, J. M.) 488–499 (Lippincott Williams & Wilkins, Philadelphia, 2000).

    Google Scholar 

  9. Kolterman, O. G. et al. J. Clin. Invest. 68, 957– 969 (1981).

    Article  CAS  Google Scholar 

  10. Miles, P. D. G. Diabetes 46, 1678–1683 ( 1997).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Medicine, University of California, 9500 Gilman Drive, San Diego, La Jolla, California, 92093-0673

    Jerrold M. Olefsky

  2. the San Diego VA HealthCare System, San Diego, California, 92161, USA

    Jerrold M. Olefsky

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  1. Jerrold M. Olefsky
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Correspondence to Jerrold M. Olefsky.

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Olefsky, J. Gene therapy for rats and mice. Nature 408, 420–421 (2000). https://doi.org/10.1038/35044177

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