The Fab' fragments of antibodies can be combined with eleven gold-atom clusters to produce the smallest gold-conjugated antibody probes yet developed.
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References
Faulk, W.P. & Taylor, G.M. Immunochemistry 8, 1081–1083 (1971).
Singer, S.J. Nature 183, 1523–1524 (1959).
Hainfeld, J.F. Science 236, 450–453 (1987).
McPartlin, M., Mason, R. & Malatesta, L. J. chem. Soc. chem. C, 334, (1969).
Bartlett, P.A., Bauer, B. & Singer, S.J. Annls Am. chem. Soc. 100, 5085–5089 (1978).
Wall, J.S., Hainfeld, J.F., Bartlett, P.A. & Singer, S. J. Ultramicrosc. 8, 397–402 (1982).
Safer, D., Hainfeld, J.F., Wall, J.S. & Riordan, J. Science 218, 290–291 (1982).
Safer, D., Bolinger, L. & Leigh, J.S. J. inorg. Biochem. 26, 77–91 (1986).
Reardon, J.E. & Frey, P.A. Biochemistry 23, 3849–3856 (1984).
Hainfeld, J.F. & Wall, J.S. in Recent Advances in Electron and Light Optical Imaging in Biology and Medicine Vol. 483 (ed. A.P. Somlyo) 181–187 (New York Academy of Seiences, New York. 1986).
Safer, D., Hainfeld, J. & Wall, J.S. Biophys. J. 47, 128a (1985).
Mosesson, M.W. et al. in Fibrinogen and Its Derivatives (eds Muller-Berghaus, G. et al.), 3–15 (Elsevier, Amsterdam, 1986).
Lipka, J.J., Hainfeld, J.F. & Wall, J.S. J. Ultrastruct. Res. 84, 120–129 (1983).
Parham, P. J. Immunol. 131, 2895–2902 (1983).
Foley, C.J., Maelia, L.E., Hainfeld, J.F. & Wall, J.S. in Proc. 45th Ann. Electron Microsc. Soc. Amer. (ed. Bailey, G.W.) 760–761 (San Francisco Press. 1987).
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Hainfeld, J. Gold cluster-labelled antibodies. Nature 333, 281–282 (1988). https://doi.org/10.1038/333281a0
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DOI: https://doi.org/10.1038/333281a0
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