Abstract
The immunoglobulin-related, T-cell specific γ gene is rearranged in a wide variety of murine T lymphocytes. We detected γ-gene transcripts in all cloned cytotoxic T lymphocytes examined but in only 1 of 11 T-helper cell lines or hybridomas. Although in cytotoxic T cells, the rearranged γ gene seems to have been assembled from the same germ-line variable and joining gene segments, the transcribed gene exhibited distinct sequence diversity near the junction between these segments.
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Kranz, D., Saito, H., Heller, M. et al. Limited diversity of the rearranged T-cell γ gene. Nature 313, 752–755 (1985). https://doi.org/10.1038/313752a0
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DOI: https://doi.org/10.1038/313752a0
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