Abstract
Fertilization of the sea urchin egg stimulates a wave of exocytosis of cortical vesicles1,2, but the mechanism by which fertilization regulates this secretion is not fully understood. We describe here experiments which suggest that polyphosphoinositide metabolism could be a factor in this regulation. We find that the cortical vesicle exocytosis in the egg of Strongylocentrotus purpuratus is preceded by a 40% increase in its content of triphosphoinositide (TPI) and a 22% increase of diphosphoinositide (DPI).
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Turner, P., Sheetz, M. & Jaffe, L. Fertilization increases the polyphosphoinositide content of sea urchin eggs. Nature 310, 414–415 (1984). https://doi.org/10.1038/310414a0
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DOI: https://doi.org/10.1038/310414a0
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