Abstract
The long-term goal of many laboratories has been to develop cellular reagents having specific reactivity against human tumour cells. Such immune cells should prove useful for defining the antigenicity of human malignancies and may have important therapeutic potential, as has been clearly shown in some animal models1. Here we describe methods of initiating continued lymphocyte cultures (CLC) having specific anti-tumour reactivity using conditioned media containing interleukin-2 (IL-2).
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Vose, B., Bonnard, G. Human tumour antigens defined by cytotoxicity and proliferative responses of cultured lymphoid cells. Nature 296, 359–361 (1982). https://doi.org/10.1038/296359a0
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DOI: https://doi.org/10.1038/296359a0
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