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Retinal projection in a non-visual area after bilateral tectal ablation in goldfish

Abstract

If, in the adult goldfish, one optic tectum is ablated, the regenerating optic axons from the contralateral retina innervate the remaining tectum, where they form a retinotopically ordered map1–3. The pathway for this induced ipsilateral projection1 coincides with many of the pathways which normally connect the two tecta, but early in regeneration the optic fibres also enter non-visual centres to which there are degenerating tectal efferent pathways to follow4. We have therefore now investigated the fate of regenerating optic axons in goldfish from which both optic tecta have been removed; they are found to innervate non-visual centres, where again they generate a retinotopic map.

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Sharma, S. Retinal projection in a non-visual area after bilateral tectal ablation in goldfish. Nature 291, 66–67 (1981). https://doi.org/10.1038/291066a0

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