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Sulfazecin and isosulfazecin, novel β-lactam antibiotics of bacterial origin

Abstract

In the long history of screening for antibiotics, fungi1,2 and actinomycetes3–8,19 have been the only producers of β-lactam antibiotics although several phytopathogenic bacteria have been reported to produce toxins with a β-lactam structure9,10. We report here the first evidence that novel monocyclic β-lactam antibiotics, sulfazecin and isosulfazecin, are produced by new species of Pseudomonas.

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Imada, A., Kitano, K., Kintaka, K. et al. Sulfazecin and isosulfazecin, novel β-lactam antibiotics of bacterial origin. Nature 289, 590–591 (1981). https://doi.org/10.1038/289590a0

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