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Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein

Abstract

The ammo-terminal signal sequence is required for initiation of transmembrane protein transfer of the Escherichia coli λ receptor protein. Mutations leading to insertion of charged amino acids into or deletion of amino acids from the hydrophobic segment of this sequence prevent export of this outer membrane protein.

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Emr, S., Hedgpeth, J., Clément, JM. et al. Sequence analysis of mutations that prevent export of λ receptor, an Escherichia coli outer membrane protein. Nature 285, 82–85 (1980). https://doi.org/10.1038/285082a0

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