Abstract
SPONTANEOUS endo-reduplication in the female germ line of hybrids has made it possible to produce several strains of isogenic Xenopus, providing one of the many features required of a laboratory animal1,2. The usefulness of Xenopus in the laboratory, however, would be improved if a gene map were available. We report here that hybrids can also be used to define linkage groups and their assignment to chromosomes. Our method is based on the possibility of creating aneuploid Xenopus which are diploid for the chromosomes of one species but have supernumerary chromosomes of a second species3. This method complements those already available4–8, and has the advantage that because traits can be monitored in the whole animal, a large repertory of markers will be made available.
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References
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KOBEL, H., DU PASQUIER, L. Hyperdiploid species hybrids for gene mapping in Xenopus. Nature 279, 157–158 (1979). https://doi.org/10.1038/279157a0
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DOI: https://doi.org/10.1038/279157a0
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