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Long-range attraction between red cells and a hydrocarbon surface

A Corrigendum to this article was published on 15 December 1977

Abstract

WE present here experimental evidence that adhesion of red cells to an oil–water interface is mediated by an attractive force acting at a distance apparently exceeding 100 nm. Although long-range forces have recently been measured between bilayer lipid lamellae in water1 and attraction between cells has been inferred from aggregation studies2,3, the long-range nature of attraction in cell studies has previously been an assumption rather than a deduction from experimental evidence. Our analysis strongly implicates a long range attractive force, but this force is extremely weak at large distances and whether it has any biological role in cell adhesion in physiological conditions is not known.

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References

  1. Le Neveu, D. M., Rand, R. P. & Parsegian, V. A. Nature 259, 601–603 (1976).

    Article  ADS  CAS  Google Scholar 

  2. Wilkins, D. J., Ottewill, R. H. & Bangham, A. D. J. theor. Biol. 2, 176–191 (1962).

    Article  CAS  Google Scholar 

  3. Curtis, A. S. G. J. Embryol. exp. Morph. 22, 305–325 (1969).

    CAS  PubMed  Google Scholar 

  4. Gingell, D. & Todd, I. J. Cell Sci. 8, 227–239 (1975).

    Google Scholar 

  5. Alamov, Y. I. Kollidnyi Zhurna, 25, 327 (1963); Engl. trans. Colloid J. (USSR) 25, 313–316 (1963).

    Google Scholar 

  6. Brenner, S. L. & Parsegian, V. A. Biophy. J. 14, 327–334 (1974).

    Article  CAS  Google Scholar 

  7. Israelachvili, J. N. & Adams, G. E. Nature 262, 774–776 (1976).

    Article  ADS  CAS  Google Scholar 

  8. Cowley, S., Fuller, N., Rand, R. P. & Parsegian, V. A. Biophys. J. 17(2) Suppl. (1977).

  9. Geigy Scientific Tables (7th edn) (CIBA—Geigy, Basle, 1970).

  10. Israelachvili, J. N. & Tabor, D. Prog. Surf. Memb. Sci. 7, 1 (1973).

    Article  CAS  Google Scholar 

  11. Parsegian, V. A. in Physical Chemistry: Enriching Topics from Colloid and Surface Science (eds van Olphen, H. & Mysels, K. J.) Ch. 4 (Theorex, La Jolla, California, 1975).

    Google Scholar 

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GINGELL, D., TODD, I. & PARSEGIAN, V. Long-range attraction between red cells and a hydrocarbon surface. Nature 268, 767–769 (1977). https://doi.org/10.1038/268767a0

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