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Are late replicating regions in polytene chromosomes of Drosophila enriched by repeated nucleotide sequences?

Nature volume 268, pages 766–767 (1977)Cite this article

Abstract

THE ordered highly coordinated pattern of replication of different bands is characteristic of salivary gland chromosomes of Drosophila1,2. During the initial stage of polytene chromosome replication labelled precursor is found over Puff/interband sections while prominent bands incorporate label later and need in general a longer time for DNA synthesis3,4. It is significant that regions of ectopic pairing in the chromosomes of D. melanogaster are of the late replicating type. We report here that late replicating DNA from Drosophila salivary gland cells reassociates after denaturation more rapidly than the bulk of the DNA from the same cells. A high level of repeated nucleotide sequences may be involved.

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Authors and Affiliations

  1. Institute of Molecular Biology, Academy of Sciences of the USSR, Vavilov Str. 32, Moscow

    MICHAIL EVGEN'EV & ANDREI LEVINE

  2. Institute of Cytology and Genetics, Siberian Branch of the Academy of Sciences of the USSR, Prospekt Nauki 10, Novosibirsk, USSR

    IRINE GUBENKO

Authors
  1. MICHAIL EVGEN'EV
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  2. ANDREI LEVINE
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  3. IRINE GUBENKO
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EVGEN'EV, M., LEVINE, A. & GUBENKO, I. Are late replicating regions in polytene chromosomes of Drosophila enriched by repeated nucleotide sequences?. Nature 268, 766–767 (1977). https://doi.org/10.1038/268766a0

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