Abstract
Analysis of the melting profile of DNA stripped of non-histone proteins and histone H1 allows definite structural conclusions to be drawn; conversely, it is possible to calculate what a particular chromatin model's melting curve will look like.
This is a preview of subscription content, access via your institution
Access options
Similar content being viewed by others
References
Li, H. J., and Bonner, J., Biochemistry, 10, 1461 (1971).
Johnson, R. S., Chan, A., and Hanlon, S., Biochemistry, 11, 4347 (1972).
Subirana, J. A., J. molec. Biol., 74, 363 (1973).
Hanlon, S., Johnson, R. S., and Chan, A., Biochemistry, 13, 3972 (1974).
Wilhelm, F. X., de Murcia, G. M., and Daune, M. P., Nucleic Acid Res., 1, 1043 (1974).
Li, H. J., Biopolymers, 12, 287 (1973).
Poland, D., and Scheraga, H. A., Theory of Helix–Coil Transitions in Biopolymers (Academic, New York, 1970).
Applequist, J., and Damle, V., J. chem. Phys., 39, 2719 (1963).
Applequist, J., and Damle, V., J. Am. Chem. Soc., 87, 1450 (1965).
Scheffler, I. E., Elson, E. L., and Baldwin, R. L., J. molec. Biol., 48, 145 (1970).
Hewish, D., and Burgoyne, L., Biochem. biophys. Res. Commun., 52, 504 (1973).
Clark, R. J., and Felsenfeld, G., Biochemistry, 13, 3622 (1974).
Axel, R., Melchior, W., Söllner-Webb, B., and Felsenfeld, G., Proc. natn. Acad. Sci. U.S.A., 71, 4101 (1974).
Sahasrabuddhe, C. G., and van Holde, K. E., J. biol. Chem., 249, 152 (1974).
Noll, M., Nature, 251, 249 (1974).
Kornberg, R. D., and Thomas, J. O., Science, 184, 865 (1974).
Kornberg, R. D., Science, 184, 868 (1974).
Oudet, P., Gros-Bellard, M., and Chambon, P., Cell, 4, 281 (1975).
Woodcock, C. L.F., and Frado, L. L. Y., Biochem. biophys. Res. Commun., 66, 403 (1975).
Tsanev, R. G., and Russev, G., Eur. J. Biochem., 43, 257 (1974).
Staynov, D. Z., Venkov, C. D., and Tsanev, R. G., C. r. Acad. bulg. Sci., 28, 525 (1975).
Staynov, D. Z., and Staynov, G., J. Sci. Inst. Ser. 2 2, 1114 (1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Staynov, D. Thermal denaturation profiles and the structure of chromatin. Nature 264, 522–525 (1976). https://doi.org/10.1038/264522a0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/264522a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
