Abstract
When cells of E.coli reach a certain critical length, which is constant in all growth conditions and equal to twice the minimum cell length, they abruptly increase their rate of elongation and divide about 20 min later. Chromosome replication terminates at about this same cell length but is not the signal for the change in rate of cell elongation.
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References
Marr, A. G., Harvey, R. J., and Trentini, W. C., J. Bact., 91, 2388–9 (1966).
Schaechter, M., Maaløe, O. and Kjeldgaard, N. O., J. gen. Microbiol., 19, 592–606 (1958).
Donachie, W. D. Nature, 219, 1077–9 (1968).
Helmstetter, C. E., Cooper, S., Pierucci, O., and Revelas, F., Cold Spring Harb. Symp. quant. Biol., 23, 809–822 (1968).
Pritchard, R. H., Barth, P. T., and Collins, J., Symp. Soc. gen. Microbiol., 19, 263–297 (1969).
Zaritsky, A., and Pritchard, R. H., J. Pact., 114, 824–837 (1973).
Zaritsky, A., J. theor. Biol., 54, 243–248 (1975).
Sargent, M. G., J. Bact., 123, 7–19 (1975).
Donachie, W. D., and Begg, K. J., Nature, 227, 1220–1224 (1970).
Powell, E. O., J. gen. Microbiol., 15, 492–511 (1956).
Teather, R. M., Collins, J. F., and Donachie, W. D., J. Bact., 118, 407–413 (1974).
Woldringh, C. L. J. Bact., 125, 248–257 (1976).
Schaechter, M., Williamson, J. P., Hood, J. R., and Koch, A. L., J. gen. Microbiol., 29, 421–434 (1962).
Donachie, W. D., Jones, N. C., and Teather, R. M., Symp. Soc. sen. Microbiol., 23, 9–44 (1973).
Maaløe, O., and Kjeldgaard, N. O., Control of Macromolecular Synthesis (Benjamin, New York, 1966).
Pierucci, O., and Helmstetter, C. E., Fedn Proc., 28, 1755–60 (1969).
Helmstetter, C. E., and Pierucci, O., J. Bact., 95, 1627–1633 (1968).
Clark, D. J., J. Bact., 96, 1214–1224 (1968).
Cooper, S., and Helmstetter, C. E., J. molec. Biol., 31, 519–540 (1968).
Jones, N. C., and Donachie, W. D., Nature new Biol., 243, 100–103 (1973).
Hoffman, B., Messer, W., Schwarz, U., J. supramolec. Struct., 1, 29–37 (1972).
Burdett, I. D. J., and Murray, R. G. E., J. Bact., 119, 1039–1056 (1974).
Smith, J. D., Barnett, L., Brenner, S., and Russell, R. L., J. molec. Biol., 54, 1–14 (1970).
Mitchison, J. M. and Vincent, W. S., Nature, 205, 987–9 (1965).
Donachie, W. D., J. Bact., 100, 260–8 (1969).
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Donachie, W., Begg, K. & Vicente, M. Cell length, cell growth and cell division. Nature 264, 328–333 (1976). https://doi.org/10.1038/264328a0
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DOI: https://doi.org/10.1038/264328a0
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