Abstract
MALIGNANT cell transformation is often accompanied by the appearance of new cell-surface antigens1–3 of four classifications (defined in ref. 3): (1) embryonic antigens (EA) that are also present on normal embryonic cells; (2) differentiation antigens (DA) so called because they are also expressed on certain normal syngeneic or allogeneic cells; (3) virus structural antigens (VSA) inserted in the surface membrane of infected cells which may or may not be transformed, and (4) tumour-specific transplantation antigens (TSTA), antigens associated with tumour rejection.
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KURTH, R., MACPHERSON, I. Avian cell transformation and the expression of avian sarcoma virus-specific tumour antigens. Nature 264, 261–263 (1976). https://doi.org/10.1038/264261a0
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DOI: https://doi.org/10.1038/264261a0
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