Abstract
SODIUM azide is known specifically to inhibit or activate a number of enzymatic activities from bacteria1 and from higher organisms2,3. Furthermore it has been shown that azide can inhibit the Mg2+-dependent ATPase of Escherichia coli in vivo4 at concentrations that do not produce any deleterious uncoupling effects on the membrane energy-transducing apparatus of the cell5. We felt that those facts could provide the basis for searching out a new type of mutation in E. coli - azide dependency.
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DANIEL, J. Azide-dependent mutants in E.coli K12. Nature 264, 90–92 (1976). https://doi.org/10.1038/264090a0
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DOI: https://doi.org/10.1038/264090a0
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