Abstract
IT is now generally accepted that T-cell differentiation is influenced by several thymic factors1,2 and that thymic reticuloepithelial cells are responsible for the production of these factors. Antibodies to a soluble thymic factor (STF) have been reported to inhibit T-cell differentiation in chicken3 and anti-thymosin globulin has been shown to inhibit the recovery of T cells in ATS-treated mice4. Such antibodies therefore can be used to advantage in studies on the modulation of T-cell functions; in this context, a preliminary knowledge of the antigenic species specificity of thymic factors becomes a primary concern.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Goldstein, A. L., Guha, A., Howe, M. L., and White, A., J. Immun., 106, 773–780 (1971).
Teodorczyk, J. A., and Potworowski, E. F., Immunology, 28, 711–717 (1975).
Potworowski, E. F., Lefebvre, D., Lussier, G., and Teodorczyk, J. A., Immunology, 28, 1115–1121 (1975).
Zatz, M. M., White, A., Schulof, R. S., and Goldstein, A. L., Ann. N Y Acad. Sci., 249, 499–504 (1975).
Potworowski, E. F., Borduas, A. G., and Lussier, G., J. Immun., 111, 1292–1294 (1973).
Herbert, G. A., Pelham, P. L., and Pittman, B., Appl. Microbiol., 25, 26–36 (1973).
Capel, P. J. A., J. immun. Meth., 5, 165–178 (1974).
Schlamowitz, M., Kaplan, M., Shaw, A. R., and Tsay, D. D., J. Immun., 114, 1590–1598 (1975).
Kuhlmann, W. D., Avrameas, S., and Ternynck, J. T., J. immun. Meth., 5, 33–48 (1974).
Schulof, R. S., Hooper, J. A., White, A., and Goldstein, A. L., Fedn Proc., 32, 962 (1973).
Goldstein, G., Ann. N. Y. Acad. Sci., 249, 177–185 (1975).
Mandi, B., and Glant, T., Nature new Biol., 246, 25 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
TEODORCZYK, J., POTOWOROWSKI, E. & SVICULIS, A. Cellular localisation and antigenic species specificity of thymic factors. Nature 258, 617–619 (1975). https://doi.org/10.1038/258617a0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/258617a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
