Abstract
WE have reported that the labelling of brain gangliosides is more extensive in chickens given labelled glucosamine and subsequently exposed to light than in other chickens kept in the dark1. The opposite result was obtained with rat brain2. These effects parallel the influence of light on the general activity of the animals, and we could not decide whether the cause was a direct or indirect stimulus on the labelling process. Similar studies with the retina may help to solve this problem, for the retina is stimulated directly by light, and it is possible, by occluding one eye, to measure labelling in different conditions of illumination in one animal. We have now done such experiments and found that the labelling of retinal gangliosides varies in response to light: these changes are not attributable to systemic effects.
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CAPUTTO, B., MACCIONI, A. & CAPUTTO, R. Light inhibits the labelling of gangliosides in chicken retina. Nature 257, 492–493 (1975). https://doi.org/10.1038/257492a0
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DOI: https://doi.org/10.1038/257492a0
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