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Effect of unsaturated fatty acids on the lipid composition of bacteriophage PM2

Abstract

A LIPID-containing bacteriophage, PM2, provides a simple model to investigate assembly of lipids and proteins into a membrane. The phospholipid in the virion, which is arranged in the form of a bilayer between nucleoprotein core and outer shell1, has a very different composition from that of the host cell, a marine bacterium, Pseudomonas BAL-31 (ref. 2). One-third of the viral lipids are derived from lipids synthesised before infection and two-thirds from lipids synthesised during viral replication3.

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TSUKAGOSHI, N., PETERSEN, M. & FRANKLIN, R. Effect of unsaturated fatty acids on the lipid composition of bacteriophage PM2. Nature 253, 125–126 (1975). https://doi.org/10.1038/253125a0

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  • DOI: https://doi.org/10.1038/253125a0

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