Abstract
A LIPID-containing bacteriophage, PM2, provides a simple model to investigate assembly of lipids and proteins into a membrane. The phospholipid in the virion, which is arranged in the form of a bilayer between nucleoprotein core and outer shell1, has a very different composition from that of the host cell, a marine bacterium, Pseudomonas BAL-31 (ref. 2). One-third of the viral lipids are derived from lipids synthesised before infection and two-thirds from lipids synthesised during viral replication3.
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References
Harrison, S. C., Caspar, D. L. D., Camerini-Otero, R. D., and Franklin, R. M., Nature new Biol., 229, 197–201 (1971).
Braunstein, S. N., and Franklin, R. M., Virology, 43, 685–695 (1971).
Tsukagoshi, N., and Franklin, R. M., Virology, 59, 408–417 (1974).
Franklin, R. M., Hinnen, R., Schãfer, R., and Tsukagoshi, N., in Membrane Proteins in Transport and Phosphorylation (edit. by Azzone, G. F., et al.) 13–22 (North-Holland Publishing Company, Amsterdam, 1974).
Camerini-Otero, R. D., and Franklin, R. M., Virology, 49, 385–393 (1972).
Hinnen, R., Schãfer, R., and Franklin, R. M., Eur. J. Biochem. (in the press).
Schãfer, R., Hinnen, R., and Franklin, R. M., Nature new Biol., 248, 681–682 (1974).
Schãfer, R., Hinnen, R., and Franklin, R. M., Eur. J. Biochem. (in the press).
Camerini-Otero, R. D., and Franklin, R. M., Virology, 49, 385–393 (1972).
Chapman, D., Owens, N. F., and Walker, D. A., Biochim. biophys. Acta, 120, 148–155 (1966).
Overath, P., and Trãube, H., Biochemistry, 12, 2625–2634 (1973).
Franklin, R. M., Salditt, M., and Silbert, J. A., Virology, 38, 627–640 (1969).
Datta, A., Braunstein, S., and Franklin, R. M., Virology, 43, 696–707 (1971).
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TSUKAGOSHI, N., PETERSEN, M. & FRANKLIN, R. Effect of unsaturated fatty acids on the lipid composition of bacteriophage PM2. Nature 253, 125–126 (1975). https://doi.org/10.1038/253125a0
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DOI: https://doi.org/10.1038/253125a0
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