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Application of β-D-glucuronides and glucose together suggests a new direction for cancer chemotherapy

Nature volume 252, pages 726–727 (1974)Cite this article

Abstract

KNOWN anti-cancer agents are unselective, attacking not only tumour cells but also other rapidly proliferating cells such as lymphocytes. Any difference between tumour and normal cells which might provide a basis for specific chemotherapy has therefore aroused interest. One such difference is the lower pH value of tumour tissue (about 6) compared with most normal tissue (about 7.3) in the presence of glucose1,2.

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  1. Institute of Pathology, Chemical Department, Erfurt Medical Academy, Nordhäuser Strasse 74, GDR-50-Erfurt

    U. BICKER

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  1. U. BICKER
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BICKER, U. Application of β-D-glucuronides and glucose together suggests a new direction for cancer chemotherapy. Nature 252, 726–727 (1974). https://doi.org/10.1038/252726a0

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