Abstract
A QUESTION of fundamental importance to structural biology is the molecular nature of the contact points which direct the protein assembly process in an extraordinarily selective and efficient manner. This problem is closely parallel to other areas of biology involving macromolecular recognition, such as enzyme/substrate specificity and antigen–antibody interaction. A promising system for the study of such structural problems is the bacteriophage T4 which is a macromolecular complex built up of discrete assemblies such as head, tail and tailfibres.
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SINGH, M., TERZAGHI, E. Selective blockage of bacteriophage T4 assembly by chemical modification. Nature 252, 321–323 (1974). https://doi.org/10.1038/252321a0
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DOI: https://doi.org/10.1038/252321a0
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