Abstract
FELDBERG and Myers1 have reported that intraventricular injections of amines produce changes in the rectal temperature of unanaesthetised cats. They noted that more than 50 µg noradrenaline produced temporary hypothermia whilst 200 µg 5-hydroxytryptamine (5HT) induced a sustained hyperthermia. These results, coupled with earlier findings that these amines were concentrated in the hypothalamus2,3, led them to speculate that the regulation of body temperature in the cat may be mediated by the release of noradrenaline and 5HT within the hypothalamus.
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METCALF, G. TRH: a possible mediator of thermoregulation. Nature 252, 310–311 (1974). https://doi.org/10.1038/252310a0
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DOI: https://doi.org/10.1038/252310a0
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