Abstract
ONSET of rapid haemoglobin formation in the blood islands of the developing chick blastodisc, both in ovo, and in vitro, commences at the stage of the 6- to 7-somite embryo1–4 which is normally attained after 28–33 h of incubation5. This phase of haemoglobin formation seems4,6 to reflect a previous covert differentiation of erythroid-progenitor cells distinct from pre-existing erythropoietic cells which form small quantities of haemoglobin as early as the primitive streak stage of development—after about 20 h incubation5.
Similar content being viewed by others
Article PDF
References
Wilt, F. H., Proc. natn. Acad. Sci. U.S.A., 48, 1582–1590 (1962).
Granick, S., and Levere, R. D., J. Cell Biol., 26, 167–176 (1965).
Wainwright, S. D., and Wainwright, L. K., Can. J. Biochem., 44, 1543–1560 (1966).
Wainwright, S. D., and Wainwright, L. K., Can. J. Biochem., 50, 1165–1173 (1972).
Hamburger, V., and Hamilton, H. L., J. Morph., 88, 49–92 (1951).
Wainwright, S. D., and Wainwright, L. K., Expl Cell Res. (in the press).
Spratt, N. T., and Haas, H., J. exp. Zool., 144, 139–157 (1960).
Miura, Y., and Wilt, F. H., Devl Biol., 19, 201–211 (1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WAINWRIGHT, S., WAINWRIGHT, L. Erythropoiesis in a cell population from the early chick blastodisc induced by diffusible product of second cell population. Nature 252, 302 (1974). https://doi.org/10.1038/252302a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/252302a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.