Abstract
EVIDENCE from electron microscopy1,2, chemical analyses of purified membranes3,4 and the use of specific membrane labelling procedures5, has demonstrated the presence of a carbohydrate-rich layer on the surface of the blood platelet. This layer contributes many of the groupings6 which give rise to the net electronegative charge on the outer surface of the plasma membrane. There is evidence to suggest that the surface-bound carbohydrate is unusual in the platelet both in terms of the large size of the constituent glycoprotein units7 and in the relatively high density of the terminal acidic monosaccharide, sialic acid8.
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NURDEN, A. Platelet macroglycopeptide. Nature 251, 151–153 (1974). https://doi.org/10.1038/251151a0
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DOI: https://doi.org/10.1038/251151a0
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