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New unstable haemoglobin (Hb Moscva, β24 (B4) Gly→Asp) found in the USSR

Abstract

THE unstable haemoglobins form a well-characterised group of human mutants which have been observed in many parts of the world1. We have recently cooperated in the study of two such haemoglobins seen in Moscow. Haematological and clinical aspects have been published in Russia2,3. One of the haemoglobins, discovered in a mildly anaemic patient who had pancreatitis (and in his son), was found to be Hb Tacoma (β30 (B12) Arg → Ser), previously described in three members of a United States Caucasian family4. As this haemoglobin has already been fully characterised5 it will not be discussed further here.

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IDELSON, L., DIDKOWSKY, N., CASEY, R. et al. New unstable haemoglobin (Hb Moscva, β24 (B4) Gly→Asp) found in the USSR. Nature 249, 768–770 (1974). https://doi.org/10.1038/249768a0

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