Abstract
THE major human histocompatibility determinants, the HL-A antigens, are cell surface markers present on lymphocytes and most other nucleated cells (compare ref. 1). Recently, work from two laboratories has indicated that HL-A antigens, released from the cell surface by means of papain digestion, are composed of two polypeptide chains2,3. The smaller of the two subunits seems to be invariant regardless of the antigenic specificity carried by the larger HL-A chain2,3 and occurs in human biological fluids4.
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ÖSTBERG, L., LINDBLOM, J. & PETERSON, P. Subunit structure of HL-A antigens on cell surface. Nature 249, 463–465 (1974). https://doi.org/10.1038/249463a0
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DOI: https://doi.org/10.1038/249463a0
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