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Hormonal regulation of presumptive mRNA in the fungus Achlya ambisexualis

Abstract

THE Oomycete fungus, Achlya ambisexualis, is one of the most primitive eukaryotes which differentiates in response to a steroid hormone1. Because it is fast growing, easy to manipulate and can be induced to undergo differentiation in a relatively synchronous manner (the entire thallus acts as target cells), Achlya lends itself to studies of the molecular control of gene activation by hormones.

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References

  1. Barksdale, A. W., Science N.Y., 166, 831–837 (1969).

    Article  ADS  CAS  Google Scholar 

  2. Barksdale, A. W., Mycologia, 62, 411–421 (1970).

    Article  CAS  PubMed  Google Scholar 

  3. Thomas, D., and Mullins, J. T., Science N.Y., 154, 84–85 (1965).

    Google Scholar 

  4. Kane, B. E., Reiskind, J. B., and Mullins, J. T., Science N.Y., 180, 1192–1193 (1973).

    Article  ADS  CAS  Google Scholar 

  5. Means, A. R., Comstock, J. P., Rosenfeld, G. C., and O'Malley, B. W., Proc. natn. Acad. Sci. U.S.A., 60, 1146–1150 (1972).

    Article  ADS  Google Scholar 

  6. Segal, S. J., Ige, R. O., Tuchimaa, P., and Burgos, M. H., Science N.Y., 181, 569–570 (1973).

    Article  ADS  CAS  Google Scholar 

  7. Brawerman, G., Mendecki, J., and Lee, S. Y., Biochemistry, 11, 637–641 (1972).

    Article  CAS  PubMed  Google Scholar 

  8. Manaham, C. O., App, A. A., and Still, C. C., Biochem. Biophys. Res. Commun., 53, 588–595 (1973).

    Article  Google Scholar 

  9. Darnell, J. E., Philipson, L., Wall, R., and Adesnik, M., Science N.Y., 174, 507–510 (1971).

    Article  ADS  CAS  Google Scholar 

  10. Singer, R. H., and Penman, S., J. molec. Biol., 78, 321–334 (1973).

    Article  CAS  PubMed  Google Scholar 

  11. Adesnik, M., Salditt, M., Thomas, W., and Darnell, J. E., J. molec. Biol., 71, 21–30 (1972).

    Article  CAS  PubMed  Google Scholar 

  12. Firtel, R. A., Jacobson, A., and Lodish, H. F., Nature new Biol., 239, 225–228 (1972).

    Article  CAS  PubMed  Google Scholar 

  13. Reed, J., and Wintersberger, E., Febs. Lett., 32, 213–217 (1973).

    Article  CAS  PubMed  Google Scholar 

  14. McLaughlin, C. S., Warner, J. R., Edmonds, M., Nakazato, H., and Vaughan, M. H., J. biol. Chem., 248, 1466–1471 (1973).

    CAS  PubMed  Google Scholar 

  15. Edmonds, M., Vaughan, M. H., and Nakazato, H., Proc. natn. Acad. Sci. U.S.A., 68, 1336–1340 (1971).

    Article  ADS  CAS  Google Scholar 

  16. Lee, S. Y., Mendecki, J., and Brawerman, G., Proc. natn. Acad. Sci. U.S.A., 68, 1331–1335 (1971).

    Article  ADS  CAS  Google Scholar 

  17. Darnell, J. E., Wall, R., and Tushinski, R. J., Proc. natn. Acad. Sci. U.S.A., 68, 1321–1325 (1971).

    Article  ADS  CAS  Google Scholar 

  18. Perry, R. P., Kelly, E., and LaTorre, J., Biochem. Biophys. Res. Commun., 48, 1593–1600 (1972).

    Article  CAS  PubMed  Google Scholar 

  19. Griffin, D. H., and Breuker, C., J. Bact., 98, 689–696 (1969).

    CAS  PubMed  PubMed Central  Google Scholar 

  20. Barksdale, A. W., and Lasure, L., Bull. Torrey Bot. Club., 100, 199–202 (1973).

    Article  CAS  Google Scholar 

  21. Jaworski, A. J., and Horgen, P. A., Arch. Biochem. Biophys., 157, 260–267 (1973).

    Article  CAS  PubMed  Google Scholar 

  22. Lin, C. Y., and Key, J. L., J. molec. Biol., 26, 237–247 (1966).

    Article  Google Scholar 

  23. Schutz, G., Beato, M., and Fiegelson, P., Biochem. Biophys. Res. Commun., 49, 690–699 (1972).

    Article  Google Scholar 

  24. O'Malley, B. W., McGuire, W. L., Kohler, P. O., and Karenman, S. G., Rec. Prog. Hormone Res., 25, 105–160 (1969).

    CAS  Google Scholar 

  25. Crane, B. G., Biochim. biophys. Acta, 72, 110–113 (1963).

    Article  Google Scholar 

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SILVER, J., HORGEN, P. Hormonal regulation of presumptive mRNA in the fungus Achlya ambisexualis. Nature 249, 252–254 (1974). https://doi.org/10.1038/249252a0

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