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Growth Hormone Releasing Factor of Microbial Origin

Nature volume 248, pages 73–75 (1974)Cite this article

Abstract

CHOLERA enterotoxin mediates specific biochemical events in both intestinal and non-intestinal tissues by stimulating adenyl cyclase and cyclic AMP1,2. Other evidence points to a role for cyclic AMP in regulating the secretion of several hormones by their respective endocrine glands3. These findings have led us to investigate whether cholera enterotoxin affects the secretory function of pituitary cells.

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Authors and Affiliations

  1. Wyeth Laboratories Inc., Radnor, Pennsylvania, 19087

    R. S. RAPPAPORT & N. H. GRANT

Authors
  1. R. S. RAPPAPORT
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  2. N. H. GRANT
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RAPPAPORT, R., GRANT, N. Growth Hormone Releasing Factor of Microbial Origin. Nature 248, 73–75 (1974). https://doi.org/10.1038/248073a0

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