Abstract
MANY pathogens escape the body's immune system because their surface antigenic determinants elicit an immune response that is too weak, temporary, or of the wrong type. A plausible solution to this type of problem is to put the antigenic determinant specific for the pathogen on a suitable carrier and present it to the host immune system in a way that will elicit a protective immune response of the right type, time course, and strength. This has been called the “chemical vaccine” approach1.
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SHIER, W. Modification of Tumour Growth with a Defined Glycoprotein Antigen. Nature 244, 99–101 (1973). https://doi.org/10.1038/244099a0
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DOI: https://doi.org/10.1038/244099a0
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