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Remarks on Virus-like Particles in Human Breast Cancer

Abstract

MANY investigators have tried to correlate the genesis of human breast cancer with the presence of a virus. In spite of many electron microscopical studies1,2, however, no convincing evidence of an association of human breast cancer with virus has been demonstrated. Last year, Moore and his colleagues3 reported that they had found particles with the same morphological characteristics as those that cause breast cancer in mice (B particles), in the milk of 5% of the American women with no history of the disease in their families; in 60% of the Americans with a history of the disease in their families ; and in 39% of Parsi women. Sarkar and Moore4 distinguish the particles in human milk with a size and shape similar to the B particles into three classes: MS-1 identical to the B particles ; MS-2 particles with the surface projections different from B, and MS-3 smooth particles. These results encouraged us to examine milk samples from Dutch women for the presence of virus-like particles.

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CALAFAT, J., HAGEMAN, P. Remarks on Virus-like Particles in Human Breast Cancer. Nature 242, 260–262 (1973). https://doi.org/10.1038/242260a0

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