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Active Transport of Lysergic Acid Diethylamide

Nature volume 240, pages 53–54 (1972)Cite this article

Abstract

ALTHOUGH it is recognized that there is little hindrance to the passage of lysergic acid diethylamide (LSD) across the blood brain barrier1, an autoradiographic study of LSD distribution in the rat brain led to speculation that the choroid plexuses are involved in the active transport of this compound between blood and cerebrospinal fluid2. It was also suggested that this tissue acts as a storage site for LSD in the brain. The purpose of this communication is to elucidate the mechanism of LSD accumulation within the choroid plexus, and clarify the role of the choroidal epithelium in the distribution of LSD between blood and brain.

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Authors and Affiliations

  1. Department of Physiology, University of California Medical Center, Los Angeles, California, 90024

    ERNEST M. WRIGHT

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  1. ERNEST M. WRIGHT
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WRIGHT, E. Active Transport of Lysergic Acid Diethylamide. Nature 240, 53–54 (1972). https://doi.org/10.1038/240053a0

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