Abstract
ASPIRIN and indomethacin inhibit the biosynthesis of prostaglandins in various tissues1–3 and similar effects have been seen with fenclozic acid4 and hydrocortisone5. This together with the growing evidence that prostaglandins, particularly PGF2α, are involved in processes leading to the termination of luteal function and to parturition in several species6–8 prompted us to investigate the effects of some anti-inflammatory agents on the time of onset and course of parturition in the rat.
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CHESTER, R., DUKES, M., SLATER, S. et al. Delay of Parturition in the Rat by Anti-Inflammatory Agents which Inhibit the Biosynthesis of Prostaglandins. Nature 240, 37–38 (1972). https://doi.org/10.1038/240037a0
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DOI: https://doi.org/10.1038/240037a0
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