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Nitrous Acid Effect on Cleavage and Development in Fertilized Frog Eggs

Nature volume 226, pages 969–970 (1970)Cite this article

Abstract

NITROUS acid causes deamination of primary amino groups attached to the ring structure of nucleic acid bases; the products have been demonstrated to cause mutations in viruses1,2, bacteria3, moulds4,5 and yeasts6. Apart from a study demonstrating chromosomal fragmentation in monocotyledon root tips treated with nitrous acid7, no report of HNO2 having an effect on higher organisms has been found.

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Authors and Affiliations

  1. Department of Zoology, Indiana University, Bloomington, Indiana

    CATHERINE S. NICHOLSON-GUTHRIE

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  1. CATHERINE S. NICHOLSON-GUTHRIE
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NICHOLSON-GUTHRIE, C. Nitrous Acid Effect on Cleavage and Development in Fertilized Frog Eggs. Nature 226, 969–970 (1970). https://doi.org/10.1038/226969a0

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  • DOI: https://doi.org/10.1038/226969a0

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