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Ovotransferrin with One Iron Atom

Nature volume 226, pages 858–859 (1970)Cite this article

Abstract

TRANSFERRINS are iron-binding proteins which can carry a maximum of two atoms of iron per mole protein. If a preparation of hen ovotransferrin is incompletely saturated with iron and subjected to isoelectric focusing three main protein fractions are observed1. The most acidic fraction (pHI 5.78) is the protein complex with two iron atoms, and the most alkaline fraction (pHI 6.73) is the metal-free protein. In the intermediate fraction (pHI 6.25) iron and protein are present in equimolar amounts and Wenn and Williams1 suggested that this fraction is a protein complex with one iron atom.

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Authors and Affiliations

  1. Department of Biochemistry, University of Bristol, University Walk, Bristol, BS8 1TD

    J. WILLIAMS, C. F. PHELPS & J. M. LOWE

Authors
  1. J. WILLIAMS
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  2. C. F. PHELPS
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  3. J. M. LOWE
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WILLIAMS, J., PHELPS, C. & LOWE, J. Ovotransferrin with One Iron Atom. Nature 226, 858–859 (1970). https://doi.org/10.1038/226858a0

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