Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Effects of Black Widow Spider Venom on the Frog Neuromuscular Junction: Effects on End-plate Potential, Miniature End-plate Potential and Nerve Terminal Spike

Abstract

Black widow spider venom causes exhaustion of miniature end-plate activity and depletes the nerve terminal of vesicles.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Grasso, A., and Poggi, P., Toxicon, 5, 1 (1967).

    Article  CAS  Google Scholar 

  2. D'Ajello, V., Mauro, A., and Bettini, S., Toxicon, 6 (in the press).

  3. D'Amour, F. E., Becker, F. E., and van Riper, W., Quart. Rev. Biol., 11, 123 (1936).

    Article  Google Scholar 

  4. Sampayo, R. R. L., J. Pharmacol. Exp. Ther., 80, 309 (1944).

    CAS  Google Scholar 

  5. Cantore, G. P., Riv. Parass., 19, 297 (1958).

    Google Scholar 

  6. Fatt, P., and Katz, B., J. Physiol., 115, 320 (1951).

    Article  CAS  Google Scholar 

  7. Katz, B., and Miledi, R., Proc. Roy. Soc., B, 155, 455 (1962).

    Article  Google Scholar 

  8. del Castillo, J., and Katz, B., J. Physiol., 124, 586 (1954).

    Article  CAS  Google Scholar 

  9. Hubbard, J., Jones, S. F., and Landau, E. M., J. Physiol., 194, 355 (1968).

    Article  CAS  Google Scholar 

  10. Blioch, Z. V., Glagoena, I. M., Lieverman, E. A., and Nemashev, V. A., J. Physiol., 199, 11 (1968).

    Article  CAS  Google Scholar 

  11. Miledi, R., and Thies, R., J. Physiol., 192, 54P (1967).

    Article  CAS  Google Scholar 

  12. Elmquist, S., and Quastel, D. M. J., J. Physiol., 177, 463 (1965).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

LONGENECKER, H., HURLBUT, W., MAURO, A. et al. Effects of Black Widow Spider Venom on the Frog Neuromuscular Junction: Effects on End-plate Potential, Miniature End-plate Potential and Nerve Terminal Spike. Nature 225, 701–703 (1970). https://doi.org/10.1038/225701a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/225701a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing