Abstract
SEX linked genes are usually expressed equally in both sexes of Drosophila, although they are present as a single dose in males and a double dose in females. This is known as dosage compensation1, a term also used when abnormal increases or decreases of gene doses are compensated. If phenotypic expression deviates from dosage compensation towards an effect proportional to the gene dose2 the term “dosage effect” is used.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Muller, H. J., Proc. Sixth Intern. Congr. Genet., 1, 213 (1932).
Stern, C., Biol. Zbl., 49, 261 (1929).
Grell, E. H., Z. Vererb., 93, 371 (1962).
Seecof, R. L., Kaplan, W. D., and Futch, D. G., Proc. US Nat. Acad. Sci., 62, 528 (1969).
Mukherjee, A. S., The Nucleus, 9, 83 (1966).
Lindsley, D. L., and Grell, E. H., Carnegie Institution Publ., 627 (1968).
Stern, C., Canad. J. Gen. Cytol., 2, 105 (1960).
Muller, H. J., Harvey Lectures, Ser. XIII, 1947–1948, 1, 165 (1950).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KORGE, G. Dosage Compensation and Effect for RNA Synthesis in Chromosome Puffs of Drosophila melanogaster. Nature 225, 386–388 (1970). https://doi.org/10.1038/225386a0
Received:
Revised:
Published:
Issue Date:
DOI: https://doi.org/10.1038/225386a0
This article is cited by
-
In situ transcription analysis of chromatin template activity of the X-chromosome of Drosophila following high molar NaCl treatment
Chromosoma (1981)
-
Comparison of in vivo and in vitro RNA synthesis on polytene chromosomes of Drosophila
Chromosoma (1976)
-
Chromosomal basis of dosage compensation in Drosophila
Chromosoma (1975)
-
Synthesis of RNA by Escherichia coli RNA polymerase on the chromosomes of Drosophila melanogaster
Chromosoma (1974)
-
The role of genetic balance in control of transcription rate in the X-chromosome of Drosophila melanogaster
Chromosoma (1974)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
