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Synthesis of Progesterone by the Mammary Gland of the Goat

Abstract

EARLIER work by R. B. H. and J. L. L. suggested that in addition to its ability to extract progesterone1, normal mammary tissue may also have the capacity of synthesizing it (ref. 2 and unpublished results of R. B. H. and J. L. L.). We have therefore investigated in two non-lactating goats, five and twelve weeks pregnant, whether progesterone could be produced by the normal mammary gland when pregnenolone was provided and, if so, its quantitative significance.

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References

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SLOTIN, C., HEAP, R., CHRISTIANSEN, J. et al. Synthesis of Progesterone by the Mammary Gland of the Goat. Nature 225, 385–386 (1970). https://doi.org/10.1038/225385a0

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