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Nature of the Peristaltic Block produced by Magnesium

Nature volume 225, pages 383–384 (1970)Cite this article

Abstract

ALTHOUGH the effect of magnesium ions on ganglionic and on neuromuscular transmission has been widely studied in recent years, little is known about the mechanism by which these ions may affect the peristaltic reflex1,2. It has been known for a long time that subcutaneous or intravenous injection of magnesium salts in rabbits abolishes or considerably diminishes peristalsis3. The present experiments therefore set out to analyse the blocking action of magnesium on peristalsis by studying its effect on acetylcholine release and on the acetylcholine receptors.

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References

  1. Hutter, O. F., and Kostial, K., J. Physiol., 124, 234 (1954).

    Article  CAS  Google Scholar 

  2. del Castillo, J., and Engbaeck, L., J. Physiol., 124, 320 (1954).

    Google Scholar 

  3. Meltzer, S. J., and Auer, J., Amer. J. Physiol., 17, 313 (1906).

    Article  Google Scholar 

  4. Trendelenburg, P., Arch. Exp. Path. Pharmacol., 81, 55 (1917).

    Article  Google Scholar 

  5. Chang, H. C., and Gaddum, J. H., J. Physiol., 79, 225 (1933).

    Article  Google Scholar 

  6. Paton, W. D. M., Brit. J. Pharmacol. Chemother., 12, 119 (1957).

    Article  CAS  Google Scholar 

  7. Paton, W. D. M., and Zar Aboo, M., J. Physiol., 194, 13 (1968).

    Article  CAS  Google Scholar 

  8. Beleslin, D., and Varagić, V., Acta Med. Iugoslav., 17, 336 (1963).

    CAS  Google Scholar 

  9. Johnson, E. S., Brit. J. Pharmacol. Chemother., 12, 555 (1963).

    Article  Google Scholar 

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Author notes

  1. D. B. BELESLIN

    Present address: Laboratory of Neuropsychology, Purdue University, Lafayette, Indiana

Authors and Affiliations

  1. Department of Pharmacology, Medical Faculty, Beograd, Yugoslavia

    D. B. BELESLIN

Authors
  1. D. B. BELESLIN
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BELESLIN, D. Nature of the Peristaltic Block produced by Magnesium. Nature 225, 383–384 (1970). https://doi.org/10.1038/225383b0

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