Abstract
To investigate the action of plant growth retardants more precisely, cell-free rat liver preparations have been used as models of plant systems1. At least some of the retardants inhibited the enzymes of the isoprenoid biosynthesizing pathway by which radioactive acetate and mevalonate are incorporated into cholesterol. Inhibition of the isoprenoid biosynthetic route2 that leads to the formation of gibberellins3 thus seemed to be one of the main effects of applying the retardants to plants4. I have expanded the earlier results and here summarize the effects of five plant growth retardants.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Paleg, L. G., and Seamark, R., Biochemistry and Physiology of Plant Growth Regulators, 389 (The Runge Press, Ottawa, 1968).
Birch, A. J., Rickard, R. W., and Smith, H., Proc. Chem. Soc., 192 (1958).
Graebe, J., Dennis, D. T., Upper, C. D., and West, C. A., J. Biol. Chem., 240, 1847 (1965).
Paleg, L. G., Kende, H., Ninnemann, H., and Lang, A., Plant Physiol., 39, 165 (1964).
Bray, G. A., Anal. Biochem., 11, 279 (1960).
Holmes, W. L., and Di Tullio, N. W., Amer. J. Clin. Nutr., 10, 310 (1962).
Moore, T. C., and Anderson, J. D., Plant Physiol., 41, 238 (1966).
Reid, W. W., Phytochemistry, 7, 451 (1968).
Dennis, D. T., and West, C. A., J. Biol. Chem., 242, 3293 (1967).
Reid, W. W., Biochem. J., 113, 37P (1969).
Cathy, H. M., Ann. Rev. Plant Physiol., 15, 271 (1964).
Reed, D. J., Moore, T. C., and Anderson, J. D., Science, 148, 1469 (1965).
Kende, H., Ninnemann, H., and Lang, A., Naturwissenschaften, 50, 599 (1963).
Dennis, D. T., Upper, C. D., and West, C. A., Plant Physiol., 40, 948 (1965).
Tahori, A. S., Zeidler, G., and Halevy, A. H., Naturwissenschaften, 52, 400 (1965).
Tahori, A. S., Zeidler, G., and Halevy, A. H., J. Sci. Food Agric., 16, 570 (1965).
Tahori, A. S., Zeidler, G., and Halevy, A. H., J. Sci. Food Agric., 16, 568 (1965).
Tahori, A. S., Zeidler, G., and Halevy, A. H., Naturwissenschaften, 52, 16 (1965).
Carlisle, D. B., Ellis, P. E., and McVeigh, L. J., Nature, 220, 189 (1968).
Zeevaart, J. A. D., Plant Physiol., 41, 856 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
PALEG, L. Differential Inhibition of Rat Liver Cholesterol Biosynthesis by Plant Growth Retardants. Nature 225, 1252–1253 (1970). https://doi.org/10.1038/2251252a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/2251252a0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
